Depot Area Homes for Sale

Depot Area Homes for Sale

Welcome to the charming Depot Area of Beaufort, South Carolina, where history meets modern living in a picturesque coastal setting. Nestled within Beaufort County, this vibrant neighborhood offers a unique blend of Southern hospitality and contemporary convenience, making it one of the most desirable places to call home in the Lowcountry.

The Depot Area is renowned for its rich historical significance, with beautifully preserved architecture and a captivating ambiance that transports you back in time. Stroll through tree-lined streets adorned with historic homes, quaint shops, and delightful eateries, all while soaking in the stunning views of the nearby waterfront. The community's proximity to the scenic Beaufort River provides residents with ample opportunities for outdoor activities, from boating to fishing and everything in between.

For those seeking a new home, the Depot Area boasts an array of charming properties that cater to diverse tastes and lifestyles. Whether you're looking for a cozy cottage, a spacious family home, or a stylish townhouse, you’ll find a variety of homes for sale that reflect the area's character and charm. With a strong sense of community and an active neighborhood association, residents enjoy a welcoming environment that fosters connections and camaraderie.

Living in the Depot Area means embracing a lifestyle rich in culture, history, and natural beauty. Experience the best of coastal living while enjoying easy access to Beaufort's vibrant downtown, renowned festivals, and a myriad of recreational opportunities. Discover your dream home in the Depot Area today and become part of this enchanting community!

Newest Depot Area Homes for Sale

$764,000
4 Beds ⋅ 4 Baths ⋅ 196518 MLS
Nestled on a quiet dead-end street in the highly sought-after neighborhood of Lyford Place, this charming Lowcountry home offers the perfect blend of comfort, convenience, and timeless Southern beauty. Located just a leisurely stroll from historic Downtown Beaufort, you'll enjoy peaceful walks beneath majestic moss-draped oak trees while taking in breathtaking views of the Beaufort River. This beautifully maintained 4-bedroom, 3.5-bathroom residence offers approximately 2,040 square feet of thoughtfully designed living space, where classic character meets modern convenience. From the moment you arrive, the serene front porch welcomes you home, inviting you to slow down and enjoy the relaxed pace of life that makes Beaufort so special. Inside, rich hardwood floors flow throughout the home, creating warmth and elegance in every room. The inviting living room serves as the heart of the home, featuring a cozy gas fireplace supplied by natural gas--perfect for gathering with family and friends on cooler evenings. A tankless water heater provides energy-efficient comfort and endless hot water. The home's layout offers flexibility for both everyday living and entertaining. The screened-in back porch provides the ideal setting for morning coffee, evening cocktails, or simply enjoying the gentle coastal breeze. Just beyond, a charming outdoor gathering area with a fire pit creates the perfect backdrop for cozy evenings under the stars. One of the property's most desirable features is the detached garage apartment, which is included in the total amount of listed sft, complete with a full bathroom and kitchenette. Whether used as a guest suite, private office, artist's studio, or space for visiting family and friends, this additional living area offers endless possibilities. Practicality meets convenience with a one-car garage and an additional carport, providing ample parking and storage. The quiet setting of Lyford Place, with no through traffic, offers a sense of privacy rarely found so close to downtown Beaufort. Outdoor enthusiasts will appreciate being just minutes from the Spanish Moss Trail, a beloved local destination for walking, biking, and enjoying the natural beauty of the Lowcountry. Along the trail, fishing spots and scenic water views provide endless opportunities to connect with nature. Combining an exceptional location, versatile living spaces, and the unmistakable charm of Beaufort, this home offers more than just a place to live--it offers a lifestyle. Whether you're enjoying a sunset stroll along Bay Street, entertaining guests around the fire pit, or exploring the nearby waterfront and trails, you'll quickly discover why Lyford Place is one of Beaufort's most treasured neighborhoods.

120 Lyford Place, Beaufort

Courtesy of Keller Williams, from Lowcountry Regional MLS.
Start Your Search
board logo

We do not attempt to independently verify the currency, completeness, accuracy or authenticity of the data contained herein. It may be subject to transcription and transmission errors. Accordingly, the data is provided on an “as is” “as available” basis only and may not reflect all real estate activity in the market. © 2026 REsides, Inc. All rights reserved. Certain information contained herein is derived from information, which is the licensed property of, and copyrighted by, REsides, Inc.

board logo

This information is deemed reliable, but not guaranteed. Neither the Lowcountry Regional MLS, nor the listing broker, nor their agents or subagents are responsible for the accuracy of the information. The buyer is responsible for verifying all information. This information is provided by the Lowcountry Regional MLS for use by its members and is not intended for use for any other purpose.